10 Powerful Facts About Phase II Metabolism That Every Healthcare Professional Must Know
1. Phase II drug metabolism Drug metabolism represents one of the most critical determinants of pharmacological response, governing drug efficacy, toxicity, and duration of action. The human body possesses sophisticated enzymatic systems designed to transform lipophilic xenobiotics into more hydrophilic, excretable metabolites. This biotransformation process is broadly classified into Phase I (functionalization) and Phase II…
