5 Critical Drug Interactions You Must Know The Role of Plasma Protein Binding
Plasma Protein Binding in Clinical Pharmacology: From Molecular Mechanisms to Therapeutic Implications Plasma protein binding (PPB) describes the reversible association between drugs and circulating proteins in the bloodstream. This interaction profoundly influences drug distribution, metabolism, excretion, and ultimately, therapeutic efficacy. While the pharmacological effect of a drug correlates most closely with its unbound (free) concentration…